Alta Stomatology is an innovative oral disease research company dedicated to developing effective solutions for tooth resorption. Tooth resorption refers to the gradual loss of dentin and cementum due to the action of odontoclasts. At Alta Stomatology, we're dedicated to offering one-stop services for tooth resorption research, including whole-genome sequencing, the development of novel therapies, and the molecular mechanisms behind this disorder. If you have any needs, please feel free to contact us.
Research on Tooth Resorption
Tooth resorption refers to the gradual loss of dentin and cementum due to the action of odontoclasts. Tooth resorption is a normal physiological process that occurs during the loss of primary dentition. However, pathological tooth resorption occurs in the permanent or secondary dentition and sometimes in the primary dentition. The most common causes of tooth resorption are pulp necrosis, trauma and inflammation caused by periodontal treatment, orthodontics, and tooth whitening.
Tooth resorption is divided into internal resorption and external resorption. Internal resorption refers to the loss of intraradicular and tubular dentin in the middle and apical third of the root canal. The best treatment for internal resorption is root canal treatment. External resorption refers to the necrosis to the dental hard tissue on the outer surface of the tooth. If external resorption progresses to the pulp, root canal treatment, surgery or even extraction may be required.
Our Services
At Alta Stomatology, we are committed to providing top-notch services in the field of oral disease research, specifically focusing on the development of root canal filling materials and core obturation materials for tooth resorption. Root canal filling materials are also called root canal sealers, which are mainly used to fill root canals during root canal treatment, ensure complete sealing of the root canals and prevent reinfection. In addition, core obturation materials are required during root canal treatment. Its purpose is to fill the bulk of the root canal space and act as a plug to prevent any leakage or ingress of foreign material. Through comprehensive materials characterization and testing, Alta Stomatology aims to discover effective tooth resorption treatment materials to improve oral health worldwide.
Development of Treatment Materials for Tooth Resorption
| Development of Root Canal Filling Materials |
Development of Core Obturation Materials |
- Zinc Oxide Eugenol Sealers
- Calcium Hydroxide Sealers
- Glass Ionomer Sealers
- Resin Sealers
- Bioceramic Sealers
|
- Silver Cones
- Gutta-Percha
- Bioceramic Materials
|
Analysis Services
- Polymerase Chain Reaction (PCR)
- Liquid Chromatography Mass Spectrometry (LC-MS)
- Electrophoresis Technology
- Enzyme Linked Immunosorbent Assay (ELISA)
Customized Research Services
With the accumulated rich R&D experience and leading technology platform, Alta Stomatology can provide customers with high-quality "one-stop" technical services. For tooth resorption diseases, we can offer a variety of customized research services, including: animal model establishment, drug screening & therapeutic efficacy testing, in vitro and in vivo study, novel drug delivery system, and oral organoid development.
Animal Model Establishment
Drug Screening
In Vitro and In Vivo Study
Novel Drug Delivery System
Oral Organoid Development
Our Diagnosis Methods
At Alta Stomatology, we understand the importance of accurate diagnosis for effective treatment of tooth resorption. That's why we have developed cutting-edge diagnosis methods to guide the diagnosis and assessment of the severity of apical periodontitis disease.
| Diagnosis Methods |
Description |
| X-ray Examination |
X-rays are used to obtain periapical films, which are used to observe the subtle morphology of the roots of individual teeth. |
| Multi-slice Spiral Computed Tomography (MSCT) |
Compared with traditional X-rays, multi-slice spiral computed tomography (MSCT) can display the anatomy of dental hard tissue and alveolar bone more clearly and realistically. |
| Cone Beam Computed Tomography (CBCT) |
Cone beam computed tomography (CBCT) is a three-dimensional imaging device commonly used for the diagnosis of oral and maxillofacial diseases. Due to its three-dimensional imaging capability and high resolution, CBCT has advantages in diagnosing pulp calcification, root resorption and revealing root canal anatomy. CBCT has become the best tool for pulp disease diagnosis, treatment monitoring and follow-up. |
References
- Galler KM, et al. Pathophysiological mechanisms of root resorption after dental trauma: a systematic scoping review. BMC Oral Health. 2021; 21(1):163.
- Abbott PV, Lin S. Tooth resorption-Part 2: A clinical classification. Dent Traumatol. 2022; 38(4):267-285.
For research use only. Not
intended for any clinical use.
