| Target: |
TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This TNF alpha antibody is un-conjugated |
| Application: |
ELISA, western blotting (WB) |
| Purification: |
Purified |
| Immunogen: |
TNF alpha antibody was raised in rabbit using highly pure recombinant human TNF-alpha as the immunogen. |
| Format: |
Lyophilized |
| Concentration: |
Lot specific |
| Buffer: |
Lyophilized from PBS, pH7.2. |
| Handling Advice: |
Avoid repeated freeze/thaw cycles. |
| Storage: |
4°C, - 20°C |
| Storage Comment: |
Store at - 20°C until reconstitution. Following reconstitution product may be stored at 4°C in the short term. For long term storage aliquot and freeze at - 20°C. |
| Alternative Name: |
TNF alpha |
| Synonyms: |
DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
| Background: |
Tumor Necrosis Factor Alpha (TNF-alpha) is a versatile pro-inflammatory cytokine released by diverse cell types such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. It is part of the TNF ligand family and transmits signals through two receptors, TNFR1 and TNFR2. TNF-alpha demonstrates cytotoxic effects on a broad range of tumor cells and is crucial for orchestrating the immune response against bacterial infections. Furthermore, TNF-alpha is implicated in the onset of septic shock, autoimmune disorders, rheumatoid arthritis, inflammation, and diabetes. |
| Molecular Weight: |
17.3 kDa (predicted detection band MW) |
