| Target: |
TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
| Binding Specificity: |
C-term |
| Reactivity: |
Human, mouse, rat, cow, dog, goat, pig, horse, rabbit, sheep |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This TNF alpha antibody is un-conjugated |
| Application: |
Western blotting (WB) |
| Sequence: |
AVSYQTKVNL LSAIKSPCQR ETPEGAEAKP WYEPIYLGGV FQLEKGDRLS |
| Characteristics: |
This is a rabbit polyclonal antibody against TNFA. It was validated on Western Blot. |
| Purification: |
Affinity purified |
| Immunogen: |
The immunogen is a synthetic peptide directed towards the C-terminal region of human TNFA. |
| Clone: |
TNF656 |
| Format: |
Liquid |
| Buffer: |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Storage: |
- 20°C |
| Storage Comment: |
For short term use, store at 2 - 8°C up to 1 week. For long term storage, store at - 20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative Name: |
TNF alpha |
| Synonyms: |
DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
| Background: |
This gene encodes a versatile proinflammatory cytokine belonging to the tumor necrosis factor (TNF) superfamily. Primarily secreted by macrophages, it exerts its effects through receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. Involved in regulating diverse biological processes such as cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation, this cytokine is implicated in various diseases including autoimmune diseases, insulin resistance, and cancer. |
