| Target: |
TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
| Binding Specificity: |
AA 187-216, C-term |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This TNF alpha antibody is un-conjugated |
| Application: |
Flow cytometry (FACS), western blotting (WB) |
| Purification: |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Immunogen: |
This TNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF. |
| Clone: |
RB33595 |
| Isotype: |
Ig fraction |
| Format: |
Liquid |
| Buffer: |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Storage: |
4°C, - 20°C |
| Storage Comment: |
TNF antibody (C-term) can be refrigerated at 2 - 8°C for up to 6 months. For long term storage, place the at - 20°C. |
| Expiry Date: |
6 months |
| Alternative Name: |
TNF alpha |
| Synonyms: |
DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
| Background: |
This gene encodes a versatile proinflammatory cytokine belonging to the tumor necrosis factor (TNF) superfamily. Primarily secreted by macrophages, it exerts its effects through receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. Involved in regulating diverse biological processes such as cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation, this cytokine is implicated in various diseases including autoimmune diseases, insulin resistance, and cancer. |
| Molecular Weight: |
25644 Da |
