| Target: |
TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
| Binding Specificity: |
AA 110-190 |
| Reactivity: |
Human, mouse, rat |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This TNF alpha antibody is un-conjugated |
| Application: |
ELISA, immunofluorescence (IF), immunohistochemistry (paraffin-embedded sections) (IHC (p)), western blotting (WB) |
| Specificity: |
TNF-α Polyclonal Antibody detects endogenous levels of TNF-α protein. |
| Purpose: |
TNF-α Polyclonal Antibody |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Immunogen: |
Synthesized peptide derived from the Internal region of human TNF-alpha at AA range: 110-190. |
| Isotype: |
IgG |
| Format: |
Liquid |
| Concentration: |
1.0 mg/mL |
| Buffer: |
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Handling Advice: |
Aliquot to avoid repeated freezing and thawing. |
| Storage: |
- 20°C |
| Storage Comment: |
Stable for one year at - 20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Alternative Name: |
TNF alpha |
| Synonyms: |
DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
| Background: |
TNF-α is a multifunctional proinflammatory cytokine belonging to the tumor necrosis factor (TNF) superfamily. It is primarily secreted by macrophages and exerts its effects by binding to its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF-α plays a crucial role in regulating various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. |
