2-1-1-green-tea-extract-1

TNF Alpha Monoclonal Antibody (MAb1) (ELISA, WB)

Cat. No.:	SPODRP00711
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Product Details

Target:	TNF alpha (Tumor necrosis factor alpha (TNF-α))
Reactivity:	Human
Host:	Mouse
Clonality:	Monoclonal
Conjugate:	This TNF alpha antibody is un-conjugated
Application:	ELISA, western blotting (WB)
Specificity:	The mouse monoclonal antibody MAb1 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
Purification:	Purified by protein-A affinity chromatography
Purity:	> 95% (by SDS-PAGE)
Sterility:	0.2 μm filtered
Immunogen:	Recombinant human TNF-alpha
Clone:	MAb1
Isotype:	IgG1
Buffer:	Azide free phosphate buffered saline (PBS), approx. pH7.4, 0.2 μm filter sterilized.
Handling Advice:	Do not freeze.
Storage:	4°C
Storage Comment:	Store at 2 - 8°C.
Alternative Name:	TNF alpha
Synonyms:	DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa.
Background:	TNF-alpha, a cytokine generated by various immune cells including monocytes, macrophages, neutrophils, NK cells, CD4+ T cells, and certain transformed cells, exists in two forms: a 17 kDa free molecule or a 26 kDa membrane protein. It readily assembles into stable trimers and other multimeric structures. Within the immune system, TNF-alpha plays a crucial regulatory role, exhibiting cytolytic and cytostatic effects against diverse tumor cells, promoting fibroblast proliferation, and aiding in neutrophil chemotaxis and phagocytosis.

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