Cat. No.: | SPODRP00699 |
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Pricey: | Inquiry |
Target: | TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
Binding Specificity: | Internal region |
Reactivity: | Human |
Host: | Mouse |
Clonality: | Monoclonal |
Conjugate: | This TNF alpha antibody is un-conjugated |
Application: | ELISA |
Purification: | The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific). |
Immunogen: | A synthesized peptide derived from human TNF alpha, corresponding to a region within the internal amino acids. |
Isotype: | IgG |
Format: | Liquid |
Buffer: | Rabbit IgG in phosphate buffered saline, pH7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
Precaution of Use: | This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
Storage: | - 20°C |
Storage Comment: | Store at - 20°C. Stable for 12 months from date of receipt. |
Alternative Name: | TNF alpha |
Synonyms: | DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
Background: | Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR, is primarily secreted by macrophages. It can induce cell death in certain tumor cell lines and acts as a potent pyrogen, causing fever either directly or by stimulating interleukin-1 secretion. This cytokine is involved in inducing cachexia and, under certain conditions, can promote cell proliferation and differentiation. |
Molecular Weight: | 26 kDa |