2-1-1-green-tea-extract-1

TNF Alpha Monoclonal Antibody (ELISA) (Human)

Cat. No.:	SPODRP00720
Size:
Quantity:
Price:	Inquiry

Product Details

Target:	TNF alpha (Tumor necrosis factor alpha (TNF-α))
Reactivity:	Human
Host:	Mouse
Clonality:	Monoclonal
Conjugate:	This TNF alpha antibody is un-conjugated
Application:	ELISA
Characteristics:	TNF (tumor necrosis factor) is a cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, under certain conditions it can stimulate cell proliferation and induce cell differentiation. TNF antibody (mAb) was raised in a Mouse host. It has been validated for use in ELISA, it has been shown to react with human samples.
Purification:	Protein A Chromatography
Immunogen:	Human TNF
Isotype:	IgG2a
Concentration:	Lot specific
Reconstitution:	Reconstitute in water to a concentration 0.1 - 1.0 mg/mL.
Buffer:	Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Precaution of Use:	This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only.
Handling Advice:	Avoid repeated freeze/thaw cycles.
Storage:	- 20°C
Storage Comment:	Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at - 20°C for up to 2 years. Keep all reagents on ice when not in storage.
Alternative Name:	TNF alpha
Synonyms:	DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa.
Background:	TNF, or Tumor Necrosis Factor, is a cytokine primarily released by macrophages. It binds to receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF can induce cell death in specific tumor cell lines and acts as a strong pyrogen that can trigger fever through its direct effects or by promoting the secretion of interleukin-1. Additionally, TNF is associated with the development of cachexia. Interestingly, under certain circumstances, TNF can also promote cell proliferation and trigger cell differentiation.
Molecular Weight:	17 kDa

Get in Touch