| Target: |
IL-6 (Interleukin 6) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Origin: |
Rhesus Monkey |
| Source: |
E. coli |
| Sequence: |
MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQ |
| Characteristics: |
The ED50 was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1.0× 107 units/mg. |
| Purity: |
> 97% by SDS-PAGE and HPLC analyses. |
| Endotoxin Level: |
Level Less than 1EU/µg of rRhIL-6 as determined by LAL method |
| Format: |
Lyophilized |
| Reconstitution: |
Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
| Storage: |
4°C |
| Alternative Name: |
Interleukin-6 (IL-6) |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin-6 (IL-6) is a multifunctional cytokine critical for host defense, as it regulates immune and inflammatory responses. It is produced by various cells, including T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes. |
| Molecular Weight: |
Approximately 21.1 kDa, a single non-glycosylated polypeptide chain containing 186 amino acids. |
