| Target: |
IL-6 (Interleukin 6) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Origin: |
Rhesus monkey |
| Source: |
E. coli |
| Application: |
Functional studies (Func) |
| Sequence: |
MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQM |
| Characteristics: |
Biological activity: fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay usingIL-6-dependent murine 7TD1 cells is less than 0.1 ng/mL, corresponding to a specific activity of > 1.0 x 107 IU/mg. |
| Purity: |
> 97% as determined by SDS-PAGE and HPLC. |
| Endotoxin Level: |
0.2 μm filtered |
| Format: |
Lyophilized |
| Buffer: |
PBS, pH7.4 |
| Storage: |
- 20°C |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Cytokine with diverse biological functions, is known for being a powerful inducer of the acute phase response. It plays a crucial role in the final differentiation of B-cells into Ig-secreting cells and is involved in the differentiation of lymphocytes and monocytes. This cytokine affects B-cells, T-cells, hepatocytes, hematopoietic progenitor cells, and CNS cells. It is essential for the generation of T(H)17 cells. |
| Molecular Weight: |
21.1 kDa |
