Cat. No.: | SPOSGO00042 |
aFGF, also known as FGF1 and HBGF-1, belongs to the fibroblast growth factor family. Its biological activity is mediated by binding to four high-affinity cell surface receptors (FGFR1–4), leading to receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF exhibits a broad spectrum of endocrine-like activities. As a multifunctional growth factor, it plays a crucial role in embryonic development and tissue repair. Furthermore, aFGF is involved in several significant physiological and pathological processes, including morphogenesis, angiogenesis, wound healing, atheromatosis, carcinogenesis, and the development and invasion of cancer. | |
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Pricey: | Inquiry |
Description: | aFGF, also known as FGF1 and HBGF-1, belongs to the fibroblast growth factor family. Its biological activity is mediated by binding to four high-affinity cell surface receptors (FGFR1–4), leading to receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF exhibits a broad spectrum of endocrine-like activities. As a multifunctional growth factor, it plays a crucial role in embryonic development and tissue repair. Furthermore, aFGF is involved in several significant physiological and pathological processes, including morphogenesis, angiogenesis, wound healing, atheromatosis, carcinogenesis, and the development and invasion of cancer. |
Species: | Canine |
Purity: | > 95% as determined by SDS-PAGE. |
Formulation: | Lyophilized from sterile PBS, pH7.4. Normally 5% - 8% trehalose, mannitol, and 0.01% Tween80 are added as protectants before lyophilization. |
Shipping Condition: | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Storage Conditions: | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
Expressed Host: | E. coli |