| Target: |
IL-6 (Interleukin 6) |
| Binding Specificity: |
AA 25-211 |
| Reactivity: |
Rat |
| Detection Method: |
Colorimetric |
| Method Type: |
Sandwich ELISA |
| Detection Range: |
62.5 - 4000 pg/mL |
| Minimum Detection Limit: |
62.5 pg/mL |
| Sample Type: |
Serum, plasma, cell culture supernatant |
| Analytical Method: |
Quantitative |
| Sensitivity: |
< 5 pg/mL |
| Application: |
ELISA |
| Specificity: |
Expression system for standard: E. coli
Immunogen sequence: P29-M212. |
| Purpose: |
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat IL-6 |
| Immunogen: |
Expression system for standard: E. coli. mmunogen sequence: F25-T211. |
| Handling Advice: |
Avoid multiple freeze-thaw cycles. |
| Storage: |
- 20°C, 4°C |
| Storage Comment: |
Store at 4°C for 6 months, at - 20°C for 12 months. |
| Expiry Date: |
12 months |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin-6 (IL-6) is a protein encoded by the IL6 gene in humans. Its functions extend beyond the hepatic acute phase response to include involvement in adipose tissue metabolism, regulation of lipoprotein lipase activity, and modulation of hepatic triglyceride secretion. IL-6 is a multifaceted cytokine crucial for bone resorption. It's been proposed to stimulate the HPA axis during immune activation, independently of hypothalamic corticotropin-releasing hormone (CRH). As an immunoregulatory cytokine, IL-6 activates a cell-surface signaling complex comprising IL-6, the IL-6 alpha-receptor (IL-6Ralpha), and the shared signaling receptor gp130. The standard product utilized in this kit is recombinant rat IL-6, comprising 188 amino acids with a molecular mass of 21.8 kDa. |
