| Description: |
The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. |
| Application: |
Western blotting 1:1000
Simple western 1:10 - 1:50 |
| Purity: |
Antibodies are purified by protein A and peptide affinity chromatography. |
| Storage: |
Supplied in 10 mM sodium HEPES (pH7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody. |
| Molecular Weight: |
289 kDa |
| Antibody Source: |
Rabbit |
| Specificity: |
Phospho-mTOR (Ser2448) antibody detects endogenous levels of mTOR only when phosphorylated at Ser2448. |
| Reactivity: |
H M R Mk |
| Sensitivity: |
Endogenous |
