| Description: |
c-Kit is a member of the subfamily of receptor tyrosine kinases that includes PDGF, CSF-1, and FLT3/flk-2 receptors. It plays a critical role in activation and growth in a number of cell types, including hematopoietic stem cells, mast cells, melanocytes, and germ cells. |
| Application: |
Western blotting 1:1000 |
| Purity: |
Antibodies are purified by protein A and peptide affinity chromatography. |
| Storage: |
Supplied in 10 mM sodium HEPES (pH7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody. |
| Molecular Weight: |
120, 145 kDa |
| Antibody Source: |
Rabbit |
| Specificity: |
Phospho-c-Kit (Tyr719) antibody detects endogenous levels of c-Kit only when phosphorylated at tyrosine 719. This antibody may cross-react with other tyrosine-phosphorylated RTKs. |
| Reactivity: |
H M |
| Sensitivity: |
Endogenous |
