Cat. No.: | SPODRP00474 |
Size: | |
Quantity: |
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Pricey: | Inquiry |
Target: | IL-12 (Interleukin 12) |
Protein Type: | Recombinant |
Origin: | Mouse |
Source: | HEK-293 cells |
Purification tag / Conjugate: | This IL12 protein is labelled with His tag. |
Sequence: | Arg23-Ala215(IL-12A) & Met23-Ser335(IL-12B) |
Purity: | > 95% as determined by Tris-Bis PAGE, > 95% as determined by HPLC. |
Endotoxin Level: | Less than 1EU per μg by the LAL method. |
Sterility: | 0.22 μm filtered |
Format: | Liquid |
Buffer: | Supplied as 0.22 μm filtered solution in PBS (pH7.4). |
Handling Advice: | Please do not repeated freeze-thaw cycles. |
Storage: | - 80°C |
Storage Comment: | Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Expiry Date: | 12 months |
Alternative Name: | IL-12 |
Synonyms: | CLMF, CLMF2, IL-12B, NKSF, NKSF2, p40, Il-12b, Il12p40, Il-12p40, Il12, IL-12p40, IL-12, LOC100217488, IL-12p35, Il-12a, Ll12a, p35, IL12p40, IL12B, IL-12 p35, interleukin 12B, interleukin 12A, interleukin 12b, interleukin 12a, Interleukin 12 level, IL12B, IL12A, Il12b, Il12a, IL12, il12a. |
Background: | Interleukin 12 (IL-12) plays a pivotal role as a versatile cytokine in coordinating the body's Th1-type immune response against cancer. Cancer is typified by uncontrolled cellular proliferation in particular areas of the body. |
Molecular Weight: | 22.80 kDa (IL - 12A) & 35.79 kDa(IL-12B). Due to glycosylation, the protein migrates to 25 - 30 kDa(IL - 12A) & 45 - 55 kDa (IL - 12B) based on Tris-Bis PAGE result. |