| Synonym(s): |
CK-13; CK13; Keratin-13; KRT13; K13; KRT-13 |
| Application: |
Immunoblotting: 1/3000 (ECL method).
Immunohistochemistry on Frozen Sections: 1/200.
Immunohistochemistry on Paraffin Sections: 1/100 (after microwave treatment).
Immunohistochemistry on Cytological Material.
Positive Control: Squamous epithelium of esophagus, gingival, palate, vagina (staining all of the suprabasal layers).
Incubation Time: 1h at RT, extended with Paraffin Sections. |
| Specificity: |
This antibody recognizes Acidic Human keratin K13 (Mr 55 000).
Excellent marker to discriminate non-cornified squamous epithelia (esophagus, vagina, gingival) from those of different origin. Negative on foot sole, scalp.
Tumors Specifically Detected: Several squamous cell carcinomas, e.g. cervix carcinoma; transitional cell carcinoma of the bladder; craniopharyngioma. |
| Formulation: |
State: Serum
State: Stabilized Liquid antiserum
Stabilizer: 0.5% BSA
Preservative: 0.09% Sodium Azide |
| Storage: |
Store the antibody undiluted at 2-8°C. |
| Reactivity: |
Human, Mouse |
| Clonality: |
Polyclonal |
| Host: |
Guinea pig |
| Conjugate: |
Unconjugated |
| Immunogen: |
Synthetic peptide (TTTSSASVTTTSNA-C) of Human keratin K13 (formerly also designated cytokeratin 13), coupled to KLH. |
| Gene Name: |
Keratin 13 |
