| Target: |
IL-6 (Interleukin 6) |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
Immunoprecipitation (IP), immunohistochemistry (IHC), neutralization (Neut), radioimmunoassay (RIA), ELISA, western blotting (WB) |
| Characteristics: |
Concentration definition: by refractometry. |
| Purification: |
Antiserum |
| Sterility: |
Sterile filtered |
| Immunogen: |
This whole rabbit serum was prepared by repeated immunizations with recombinant human IL-6 produced in E. coli. Immunogentype:Recombinant |
| Format: |
Liquid |
| Concentration: |
80 mg/mL |
| Buffer: |
0.02 M potassium phosphate, 0.15 M sodium chloride, pH7.2. |
| Storage: |
- 20°C |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
The anti-IL-6 antibody targets IL-6, a secreted cytokine renowned for its diverse biological functions. IL-6 stands as a potent trigger for the acute phase response, pivotal in steering B-cell differentiation towards Ig-secreting cells, and pivotal in lymphocyte and monocyte differentiation. Moreover, IL-6 fosters the growth of myeloma and plasmacytoma, promotes nerve cell differentiation, and exerts influence on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells, and central nervous system cells. Notably, IL-6 serves as a myokine, released into the bloodstream post-muscle contraction, enhancing fat breakdown and refining insulin resistance. |
