| Target: |
IL-6 (Interleukin 6) |
| Reactivity: |
Rat |
| Host: |
Goat |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
ELISA, western blotting (WB) |
| Purification: |
Purified |
| Immunogen: |
IL6 antibody was raised in goat using highly pure recombinant rat IL-6 as the immunogen. |
| Format: |
Lyophilized |
| Concentration: |
Lot specific |
| Buffer: |
Lyophilized from PBS, pH7.2. |
| Handling Advice: |
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. |
| Storage: |
4°C, - 20°C |
| Storage Comment: |
Store at - 20°C until reconstitution. Following reconstitution product may be stored at 4°C in the short term. For long term storage aliquot and freeze at - 20°C. |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
IL6 is a multifunctional cytokine pivotal in orchestrating immune defenses and modulating inflammatory reactions within the body. It is synthesized by various cell types including T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes, showcasing its wide-ranging biological impact. IL6 fosters B-cell differentiation and facilitates antibody generation, collaborates with IL3 to support megakaryocyte maturation and platelet formation, triggers the synthesis of acute-phase proteins in the liver, and exerts control over bone metabolism. Its signaling pathway operates through the IL6 receptor system, comprising two components: IL6R alpha and gp130. |
| Molecular Weight: |
21.7 kDa (predicted detection band MW) |
