| Target: |
IL-6 (Interleukin 6) |
| Binding Specificity: |
AA 30-212 |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
ELISA, immunohistochemistry, western blotting (WB) |
| Cross-Reactivity: |
Human, mouse |
| Purification: |
> 95%, protein G purified. |
| Immunogen: |
Recombinant human interleukin-6 protein (30-212AA). |
| Isotype: |
IgG |
| Format: |
Liquid |
| Buffer: |
Preservative: 0.03% proclin 300.
Constituents: 50% glycerol, 0.01 M PBS, PH7.4. |
| Precaution of Use: |
This product contains a poisonous and hazardous substance which should be handled by trained staff only. |
| Handling Advice: |
Avoid repeated freeze. |
| Storage: |
- 20°C, - 80°C |
| Storage Comment: |
Upon receipt, store at - 20°C or - 80°C. |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Cytokine boasts a diverse array of biological functions. It serves as a potent trigger for the acute phase response and plays a crucial role in guiding B-cells towards their final differentiation into Ig-secreting cells. Moreover, it actively participates in the differentiation of lymphocytes and monocytes. Additionally, it stimulates the growth of myeloma and plasmacytoma, while also promoting the differentiation of nerve cells. Its influence extends to B-cells, T-cells, hepatocytes, hematopoietic progenitor cells, and cells within the central nervous system. Furthermore, it operates as a myokine, being released into the bloodstream following muscle contraction. Its actions include enhancing the breakdown of fats and improving insulin resistance. |
