| Target: |
IL-6 (Interleukin 6) |
| Reactivity: |
Human, mouse, rat, chicken, cow, horse, pig, rabbit, sheep |
| Host: |
Mouse |
| Clonality: |
Monoclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
ELISA, western blotting (WB) |
| Purification: |
Unpurified Ascites |
| Immunogen: |
Purified recombinant fragment of human IL-6 expressed in E. coli. |
| Isotype: |
IgG1 |
| Format: |
Liquid |
| Buffer: |
Ascitic fluid containing 0.03% sodium azide. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Handling Advice: |
Avoid repeated freeze/thaw cycles. |
| Storage: |
- 20°C |
| Storage Comment: |
Aliquot and store at -20°C. |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin 6 (IL-6) is a cytokine predominantly generated by activated monocytes, fibroblasts, and epithelial cells. Its biological activities stem from its interaction with a cell surface signaling complex consisting of IL6, IL6RA, and the shared signaling receptor gp130. IL-6 is pivotal in the terminal differentiation of B-cells into Ig-secreting cells, promoting the growth of myeloma and plasmacytoma, and facilitating the differentiation of nerve cells. Furthermore, IL-6 serves as a crucial regulator of the acute phase reaction. |
