| Target: |
IL-18 (Interleukin 18) |
| Binding Specificity: |
AA 1-193 |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-18 antibody is un-conjugated |
| Application: |
ELISA, immunohistochemistry (IHC) |
| Cross-Reactivity: |
Human |
| Purification: |
> 95%, protein G purified. |
| Immunogen: |
Recombinant Human Interleukin-18 protein (1-193AA). |
| Isotype: |
IgG |
| Format: |
Liquid |
| Buffer: |
Preservative: 0.03% proclin 300.
Constituents: 50% glycerol, 0.01 M PBS, PH7.4. |
| Precaution of Use: |
This product contains a poisonous and hazardous substance which should be handled by trained staff only. |
| Storage: |
- 20°C, - 80°C |
| Storage Comment: |
Upon receipt, store at - 20°C or - 80°C. Avoid repeated freeze. |
| Alternative Name: |
IL18 |
| Synonyms: |
Igif, Il-18, IL-18, IGIF, ChIL-18, IL-1g, IL1F4, IL18, interleukin 18, Il18, IL18. |
| Background: |
A cytokine with proinflammatory properties primarily engages in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. By binding to IL18R1 and IL18RAP, it forms a signaling ternary complex, activating NF-kappa-B and prompting the synthesis of inflammatory mediators. It synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. |
