Cat. No.: | SPODRP00526 |
Size: | |
Quantity: |
|
Pricey: | Inquiry |
Target: | IL-18 (Interleukin 18) |
Binding Specificity: | AA 1-193 |
Reactivity: | Human |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | This IL-18 antibody is conjugated to FITC |
Application: | ELISA |
Cross-Reactivity: | Human |
Purification: | > 95%, protein G purified. |
Immunogen: | Recombinant human interleukin-18 protein (1-193AA). |
Isotype: | IgG |
Format: | Liquid |
Buffer: | Preservative: 0.03% proclin 300. Constituents: 50% glycerol, 0.01 M PBS, PH7.4. |
Precaution of Use: | This product contains a poisonous and hazardous substance which should be handled by trained staff only. |
Handling Advice: | Avoid repeated freeze. |
Storage: | - 20°C, - 80°C |
Storage Comment: | Upon receipt, store at - 20°C or - 80°C. |
Alternative Name: | IL18 |
Synonyms: | Igif, Il-18, IL-18, IGIF, ChIL-18, IL-1g, IL1F4, IL18, interleukin 18, Il18, IL18. |
Background: | A cytokine with proinflammatory properties, primarily engaged in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. When it binds to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, prompting the production of inflammatory mediators. It collaborates with IL12/interleukin-12 to stimulate IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. |