| Synonyms: |
CLMF, CLMF2, IL-12B, NKSF, NKSF2, p40, Il-12b, Il12p40, Il-12p40, Il12, IL-12p40, IL-12, LOC100217488, IL-12p35, Il-12a, Ll12a, p35, IL12p40, IL12B, IL-12 p35, interleukin 12B, interleukin 12A, interleukin 12b, interleukin 12a, Interleukin 12 level, IL12B, IL12A, Il12b, Il12a, IL12, il12a. |
| Background: |
IL-12 is a powerful regulator of cell-mediated immune responses, stimulating the production of IFN-gamma by NK and T cells. It is produced by activated monocytes/macrophages, B lymphocytes, and connective tissue mast cells. IL-12's biological activities include promoting the growth and activity of activated NK cells, CD4+ cells, and CD8+ cells, as well as inducing the development of IFN-gamma-producing Th1 cells. |
