| Target: |
IL-1 beta (Interleukin 1, beta (IL-1β)) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Origin: |
Rhesus monkey |
| Source: |
E. coli |
| Application: |
Functional studies (Func) |
| Specificity: |
0.2 μm filtered |
| Sequence: |
APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS |
| Characteristics: |
Biological activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10.G4.1 cells is less than 10 pg/mL, corresponding to a specific activity of >1 x 108 IU/mg. |
| Purity: |
>98% as determined by SDS-PAGE and HPLC. |
| Sterility: |
0.2 μm filtered |
| Format: |
Lyophilized |
| Buffer: |
PBS, pH7.4 |
| Storage: |
- 20°C |
| Alternative Name: |
IL1B |
| Synonyms: |
IL-1, IL1-BETA, IL1F2, IL-1BETA, IL1beta, il1-b, zgc:111873, IL-1B, IL-1beta, Il-1b, IL1B, IL-1 beta, IL-1b, interleukin 1 beta, interleukin 1, beta, IL1B, il1b, Il1b. |
| Background: |
IL-1, crafted by activated macrophages, kickstarts thymocyte growth by triggering the release of IL-2, fostering B-cell development and expansion, and igniting fibroblast growth factor action. These proteins of IL-1 play pivotal roles in inflammation, tagged as internal fever-inducers, and are noted for spurring the discharge of prostaglandin and collagenase from synovial cells. |
| Molecular Weight: |
17.3 kDa |
