| Target: |
IFNB1 (Interferon, beta 1, Fibroblast) |
| Reactivity: |
Human |
| Host: |
Goat |
| Clonality: |
Polyclonal |
| Conjugate: |
This IFNB1 antibody is un-conjugated |
| Application: |
Neutralization (Neut), ELISA, western blotting (WB) |
| Characteristics: |
Affinity purified Goat polyclonal IFN beta antibodyBioactivity: The exact concentration of antibody required to neutralize human interferon beta activity is dependent on the cytokine concentration, cell type, growth conditions and type of activity studied. The neutralization dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 for this antibody on human (HeLa/EMCV) cells is approx. 0.05- 0.2 µg/mL in the presence of 10 ng/mL of human interferon beta, based on the anti-viral assay. The specific conditions are described in the figure legends. |
| Purification: |
Purified |
| Immunogen: |
IFN beta antibody was raised in goat using human interferon beta as the immunogen. |
| Isotype: |
IgG |
| Format: |
Lyophilized |
| Concentration: |
Lot specific |
| Reconstitution: |
Reconstitute in sterile PBS. |
| Buffer: |
Lyophilized from PBS with 5% trehalose. |
| Handling Advice: |
Avoid repeated freeze/thaw cycles.
dilute only prior to immediate use. |
| Storage: |
- 20°C |
| Storage Comment: |
Aliquot and store at -20°C. |
| Alternative Name: |
IFN beta |
| Synonyms: |
IFB, IFF, IFNB, IFN-beta, Ifb, Ifnb, IFNb, interferon beta 1, interferon beta 1, fibroblast, interferon, beta 1, fibroblast, IFNB1, Ifnb1. |
| Background: |
Interferons (IFNs) are proteins produced and secreted by lymphocytes upon encountering pathogens like viruses, bacteria, parasites, or tumor cells. They facilitate intercellular communication, activating the immune system's protective mechanisms to eliminate pathogens or tumors. |
