| Target: |
IFNA (Interferon alpha) |
| Binding Specificity: |
AA 101-189 |
| Reactivity: |
Mouse |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IFNA antibody is un-conjugated |
| Application: |
ELISA, immunofluorescence (cultured cells) (IF (cc)), immunofluorescence (paraffin-embedded sections) (IF (p)), immunohistochemistry (frozen sections) (IHC (fro)), immunohistochemistry (paraffin-embedded sections) (IHC (p)), western blotting (WB) |
| Specificity: |
This antibody will detect Human IFN-Alpha subtypes 2,4,5,6,7,8,10,14,16,17 and has lower affinity for IFNA1/13. this antibody will detect Mouse IFN-Alpha subtypes 1,2,5,7,12,13,14,16 |
| Purification: |
Purified by protein A. |
| Immunogen: |
KLH conjugated synthetic peptide derived from human IFNA4. |
| Isotype: |
IgG |
| Format: |
Liquid |
| Concentration: |
1 μg/μL |
| Buffer: |
0.01 M TBS (pH7.4) with 1% BSA, 0.03% proclin300 and 50% glycerol. |
| Precaution of Use: |
This product contains a poisonous and hazardous substance, which should be handled by trained staff only. |
| Storage: |
- 20°C |
| Storage Comment: |
Store at - 20°C for one year. Avoid repeated freeze/thaw cycles. |
| Alternative Name: |
IFN-alpha |
| Background: |
Interferon-alpha (IFN-alpha), also referred to as IFN-a, IFNA, and Interferon-alpha, is classified as a type I interferon and comprises 13 subtypes: IFN-alpha 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21. These subtypes are primarily synthesized by cells infected with viruses upon detection of danger signals like viral DNA or RNA. Upon binding to its receptor, IFN-alpha triggers an antiviral response, while also demonstrating anti-tumor effects. Plasmacytoid dendritic cells are notably significant producers of type I interferons. |
