| Target: |
IFNA (Interferon alpha) |
| Binding Specificity: |
AA 101-189 |
| Reactivity: |
Mouse |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IFNA antibody is conjugated to alexa fluor 555 |
| Application: |
Immunofluorescence (cultured cells) (IF (cc)), immunofluorescence (paraffin-embedded sections) (IF (p)) |
| Specificity: |
This antibody will detect human IFN-Alpha subtypes 2,4,5,6,7,8,10,14,16,17 and has lower affinity for IFNA1/13. this antibody will detect mouse IFN-Alpha subtypes 1,2,5,7,12,13,14,16 |
| Predicted Reactivity: |
Human |
| Purification: |
Purified by protein A. |
| Immunogen: |
KLH conjugated synthetic peptide derived from human IFNA4. |
| Isotype: |
IgG |
| Format: |
Liquid |
| Concentration: |
1 μg/μL |
| Buffer: |
Aqueous buffered solution containing 0.01 M TBS (pH7.4) with 1% BSA, 0.03% proclin300 and 50% glycerol. |
| Precaution of Use: |
This product contains a poisonous and hazardous substance, which should be handled by trained staff only. |
| Storage: |
- 20°C, - 80°C |
| Storage Comment: |
Store at - 20°C, for long storage, store at - 80°C. Avoid multiple freeze-thaw cycles. |
| Alternative Name: |
IFN-alpha |
| Background: |
Interferon-alpha, also referred to as IFN-alpha, IFN-a, IFNA, is a type I interferon encompassing 13 subtypes: IFN-alpha 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21. These subtypes are predominantly synthesized by virus-infected cells upon detection of danger signals like viral DNA or RNA. Upon binding to its receptor, IFN-alpha triggers an antiviral response, with demonstrated anti-tumor effects as well. Plasmacytoid dendritic cells are significant contributors to the production of type I interferons. |
