Target: |
IFNA (Interferon alpha) |
Reactivity: |
Human |
Host: |
Mouse |
Clonality: |
Monoclonal |
Conjugate: |
This IFNA antibody is un-conjugated |
Application: |
ELISA, western blotting (WB) |
Purification: |
Protein G affinity chromatography |
Immunogen: |
Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody. |
Clone: |
2-52 |
Isotype: |
IgG1 kappa |
Format: |
Liquid |
Concentration: |
0.2 mg/mL |
Buffer: |
PBS with 0.1 mg/mL BSA and 0.05% sodium azide. |
Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
Storage: |
- 20°C |
Storage Comment: |
Aliquot and Store at - 20°C. Avoid freez-thaw cycles. |
Alternative Name: |
Interferon alpha |
Background: |
This monoclonal antibody (mAb) specifically targets human interferon alpha 1 and does not exhibit cross-reactivity with human interferon alpha 2. Interferons are widely recognized therapeutic agents due to their anti-tumor and anti-viral properties, as well as their ability to modulate the immune system. These cytokines exert their effects by binding to the Type 1 Interferon-α receptor (IFNAR1). The regulation of this receptor is pivotal in determining both the intensity and duration of cytokine signaling. This regulatory process is influenced by the phosphorylation of Serine 535 and 539 residues within the IFNAR1 protein. |