Cat. No.: | SPODRP01163 |
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Pricey: | Inquiry |
Target: | IFNA (Interferon alpha) |
Binding Specificity: | AA 101-189 |
Reactivity: | Human |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | This IFNA antibody is conjugated to Biotin |
Application: | Immunohistochemistry (frozen sections) (IHC (fro)), immunohistochemistry (paraffin-embedded sections) (IHC (p)), western blotting (WB) |
Specificity: | This antibody will detect all 13 subtypes of human IFN-Alpha |
Predicted Reactivity: | Human |
Purification: | Purified by protein A. |
Immunogen: | KLH conjugated synthetic peptide derived from human IFNA1. |
Isotype: | IgG |
Format: | Liquid |
Concentration: | 1 μg/μL |
Buffer: | Aqueous buffered solution containing 0.01 M TBS (pH7.4) with 1% BSA, 0.03% proclin300 and 50% glycerol. |
Precaution of Use: | This product contains a poisonous and hazardous substance, which should be handled by trained staff only. |
Storage: | - 20°C |
Storage Comment: | Store at - 20°C. |
Alternative Name: | IFN-alpha |
Background: | Interferon-alpha, also referred to as IFN-alpha, IFN-a, IFNA, is a type I interferon encompassing 13 subtypes: IFN-alpha 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21. These subtypes are predominantly synthesized by virus-infected cells upon detection of danger signals like viral DNA or RNA. Upon binding to its receptor, IFN-alpha triggers an antiviral response, with demonstrated anti-tumor effects as well. Plasmacytoid dendritic cells are significant contributors to the production of type I interferons. |