Cat. No.: | SPODRP00859 |
Size: | |
Quantity: |
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Pricey: | Inquiry |
Target: | TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
Biological Activity: | Active |
Protein Type: | Recombinant |
Protein Characteristics: | Full length |
Origin: | Human |
Source: | E. coli |
Characteristics: | Purified recombinant Human TNF alpha protein expression system: E. coli. Bioactivity: The ED50 was determined by the cytolysis of murine L929 cells in the presence of actinomycin D. |
Purification: | Proprietary chromatographic technique |
Purity: | > 98% |
Format: | Lyophilized |
Reconstitution: | Reconstitute in water to a concentration of 0.1 - 1.0 g/mL. |
Buffer: | Lyophilized from 20 mM PBS, pH 7.2, with 10 mM NaCl. |
Handling Advice: | Avoid repeated freeze/thaw cycles. |
Storage: | 4°C, - 20°C |
Storage Comment: | Store at 4°C until reconstitution. Following reconstitution aliquot and freeze at - 20°C for long term storage. |
Alternative Name: | TNF-alpha |
Synonyms: | DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
Background: | Tumor necrosis factor (TNF) is a cytokine that plays a key role in systemic inflammation and stimulates the acute phase reaction as part of a larger group of cytokines. Primarily secreted by macrophages, TNF induces apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis, and viral replication. It is also involved in lipid metabolism and coagulation. |
Molecular Weight: | 17,483 Da |