| Target: |
TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
| Protein Type: |
Recombinant |
| Origin: |
Human |
| Source: |
HEK-293 cells |
| Purification tag / Conjugate: |
This TNF alpha protein is labelled with DYKDDDDK-His Tag. |
| Application: |
Antibody production (AbP), standard (STD) |
| Characteristics: |
Recombinant human tumor necrosis factor (TNF-alpha) protein expressed in HEK293 cells. Produced with end-sequenced ORF clone. |
| Purity: |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Concentration: |
50 μg/mL |
| Buffer: |
1 x PBS, pH7.4, 10% glycerol. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
| Storage: |
- 80°C |
| Storage Comment: |
Store at - 80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2 - 3 freeze thaw cycles are recommended. |
| Alternative Name: |
Tumor necrosis factor alpha (TNFa) |
| Synonyms: |
DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
| Background: |
This gene encodes a versatile proinflammatory cytokine within the tumor necrosis factor (TNF) superfamily. It's primarily secreted by macrophages and functions through binding to its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. Involved in regulating various biological processes such as cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation, this cytokine is implicated in numerous diseases, including autoimmune disorders, insulin resistance, and cancer. |
| Molecular Weight: |
21 kDa |
