Human TNF Apha Protein (AA 114-281, Soluble)

2-1-1-green-tea-extract-1

Human TNF Apha Protein (AA 114-281, Soluble)

Cat. No.: SPODRP00883
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Product Details

Target: TNF alpha (Tumor necrosis factor alpha (TNF-α))
Protein Type: Recombinant
Protein Characteristics: AA 114-281, soluble
Origin: Human
Source: E. coli
Characteristics: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 169 AA (114-281) and having a molecular mass of 19.6 kDa.
Purification: Purified by proprietary chromatographic techniques.
Purity: > 95% (SDS-PAGE)
Endotoxin Level: < 0.1 EU/μg purified protein
Format: Liquid
Buffer: TRAIL in 20 mM Tris-HCl pH7.5, 300 mM NaCl, 0.01 mM DTT and 10% glycerol.
Storage: - 20°C
Alternative Name: Tumor necrosis factor alpha (TNFa)
Synonyms: DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa.
Background: TNF-related apoptosis-inducing ligand (TRAIL) is a molecule that triggers apoptosis. It functions as a type II transmembrane protein and shares homology with other members of the tumor necrosis factor family. In humans, the gene responsible for TRAIL is situated on chromosome 3q26. TRAIL interacts with death receptors DR4 and DR5, initiating caspase-8-dependent apoptosis. While TRAIL predominantly induces apoptosis in transformed and tumor cells, it typically spares normal cells, despite being expressed at considerable levels in most normal tissues.
Molecular Weight: 35.1 kDa

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