| Target: |
IL-6 (Interleukin 6) |
| Protein Type: |
Recombinant |
| Origin: |
Human |
| Source: |
E. coli |
| Sequence: |
Val30-Met212 |
| Purity: |
> 95% as determined by Tris-Bis PAGE, > 90% as determined by HPLC. |
| Endotoxin Level: |
Less than 1EU per μg by the LAL method. |
| Sterility: |
0.22 μm filtered |
| Format: |
Lyophilized |
| Reconstitution: |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water. |
| Buffer: |
Lyophilized from 0.22 μm filtered solution in PBS (pH7.4). Normally 5% trehalose is added as protectant before lyophilization. |
| Storage: |
4°C, - 80°C |
| Storage Comment: |
Reconstituted protein stable at - 80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Expiry Date: |
12 months |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin-6 (IL-6) is a cytokine involved in various biological processes including the acute phase response, inflammation, hematopoiesis, bone metabolism, and cancer advancement. It interacts with both the interleukin-6 receptor and glycoprotein, exerting its effects through complex molecular interactions. |
| Molecular Weight: |
The protein has a predicted 20.8 kDa same as Tris-Bis PAGE result. |
