| Target: |
IL-6 (Interleukin 6) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Origin: |
Human |
| Source: |
E. coli |
| Purification tag / Conjugate: |
This IL-6 protein is labelled with His tag. |
| Application: |
Antibody production (AbP), functional studies (Func), protein interaction (PI), standard (STD) |
| Specificity: |
Optimal preservation of protein structure, post-translational modifications and functions. |
| Characteristics: |
Recombinant human interleukin-6 / IL6 (C-term His tag) protein expressed in E. coli. Produced with end-sequenced ORF clone tested for bioactivity. |
| Purity: |
> 95% as determined by SDS-PAGE and Coomassie blue staining |
| Endotoxin Level: |
< 0.1 EU per μg protein as determined by LAL test |
| Buffer: |
Lyophilized from a 0.2 μM filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH5.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
| Storage: |
- 80°C |
| Storage Comment: |
Store at - 80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2 - 3 freeze thaw cycles are recommended. |
| Alternative Name: |
Interleukin-6,il6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
This genetic sequence instructs the production of a cytokine crucial for inflammation regulation and B cell development. Moreover, the resulting protein serves as a natural fever inducer in individuals with autoimmune conditions or infections. It is predominantly synthesized at sites of both acute and chronic inflammation, where it triggers a transcriptional inflammatory reaction via the interleukin 6 receptor, alpha. The activity of this gene is associated with numerous inflammation-related diseases. |
| Molecular Weight: |
20.9 kDa |
