| Target: |
IL-6 (Interleukin 6) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Protein Characteristics: |
AA 30-212 |
| Origin: |
Human |
| Source: |
HEK-293 cells |
| Sequence: |
AA 30-212 |
| Characteristics: |
This protein carries no "tag". The protein has a calculated MW of 20.8 kDa. The protein migrates as 24-27 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation. |
| Purity: |
> 90% as determined by SDS-PAGE. |
| Endotoxin Level: |
Less than 1EU per μg by the LAL method. |
| Sterility: |
0.22 μm filtered |
| Format: |
Lyophilized |
| Buffer: |
PBS, pH7.4 |
| Handling Advice: |
Please avoid repeated freeze-thaw cycles. |
| Storage: |
- 20°C |
| Storage Comment: |
No activity loss was observed after storage at: In lyophilized state for 1 year (4°C), After reconstitution under sterile conditions for 3 months (- 70°C). |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin 6 (IL-6), also referred to as HGF, BSF2, HSF, IFNB2, and IL-6, was initially recognized as a factor driving B cell differentiation. It serves as a versatile cytokine, governing immune responses, hematopoiesis, acute phase reactions, and inflammatory processes. Produced by a variety of cells including T cells, macrophages, monocytes, fibroblasts, and endothelial cells, IL-6 plays a pivotal role in stimulating immune reactions to trauma, particularly in cases of burns or tissue damage leading to inflammation. |
| Molecular Weight: |
20.8 kDa |
