| Target: |
IL-6 (Interleukin 6) |
| Reactivity: |
Human |
| Detection Method: |
Colorimetric |
| Method Type: |
Sandwich ELISA |
| Sample Type: |
Serum, plasma, cell culture supernatant |
| Sensitivity: |
1.0 pg/mL |
| Application: |
ELISA |
| Plate: |
Pre-coated |
| Characteristics: |
IL-6 ELISA kit (human) (Interleukin-6, IL-6, B-cell stimulatory factor 2, CTL differentiation factor, CDF, hybridoma growth factor, interferon beta-2, IFN-beta-2, IL6, IFNB2). |
| Storage: |
4°C, - 20°C |
| Storage Comment: |
4°C, - 20°C |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
Interleukin 6 (IL-6), also referred to as interferon-beta 2, 26kD protein, and B cell stimulatory factor-2 (BSF-2), is a multifunctional alpha-helical cytokine with diverse roles in acute phase responses, inflammation, hematopoiesis, bone metabolism, and cancer progression. Its activity is pivotal in orchestrating the transition from acute inflammation to either acquired immunity or chronic inflammatory diseases. IL-6 is produced by various cell types as a phosphorylated and variably glycosylated molecule weighing between 22kD to 28kD. The mature human IL-6 consists of 183 amino acids and shares 41% sequence identity with its counterparts in mice and rats. Through alternate splicing, IL-6 generates several isoforms with internal deletions, some of which possess antagonistic properties. |
