| Target: |
IL-18 (Interleukin 18) |
| Reactivity: |
Human |
| Detection Method: |
Colorimetric |
| Method Type: |
Sandwich ELISA |
| Detection Range: |
15.6 pg/mL - 1000 pg/mL |
| Minimum Detection Limit: |
15.6 pg/mL |
| Sample Type: |
Cell culture supernatant, plasma, serum |
| Analytical Method: |
Quantitative |
| Sensitivity: |
< 1 pg/mL |
| Application: |
ELISA |
| Plate: |
Pre-coated |
| Specificity: |
Expression system for standard: E.coli
Immunogen sequence: Y33-D197 |
| Purpose: |
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human IL-18 |
| Immunogen: |
Expression system for standard: E. coli. Immunogen sequence: Y33-D197. |
| Handling Advice: |
Avoid multiple freeze-thaw cycles. |
| Storage: |
- 20°C, 4°C |
| Storage Comment: |
Store at 4°C for 6 months, at - 20°C for 12 months. |
| Expiry Date: |
12 months |
| Alternative Name: |
IL18 |
| Synonyms: |
Igif, Il-18, IL-18, IGIF, ChIL-18, IL-1g, IL1F4, IL18, interleukin 18, Il18, IL18. |
| Background: |
Interleukin(IL)-18, also known as Interferon-gamma-inducing factor (IGIF), enhances the natural killer (NK) cell activity in spleen cells. Encoded by a gene yielding a precursor protein of 192 amino acids and a mature protein of 157 amino acids, IL-18 is a recently identified cytokine influencing both T helper type 1 (Th1) and Th2 responses. It serves as a potent proinflammatory cytokine with potential implications in atherogenesis. Elevated expression of IL-18 is observed in atherosclerotic plaques compared to healthy arterial tissues, predominantly localized within plaque macrophages. |
