| Target: |
IFNB1 (Interferon, beta 1, Fibroblast) |
| Biological Activity: |
Active |
| Protein Type: |
Recombinant |
| Origin: |
Human |
| Source: |
E. coli |
| Characteristics: |
Purified recombinant human IFN beta protein expression system: E. coli.
Bioactivity: The EC50 for interferon in a cytopathic effect inhibition assay is ~1 U/mL (human) and ~5 U/mL (bovine). |
| Purity: |
> 98% pure |
| Format: |
Liquid |
| Concentration: |
1000000 U/mL |
| Buffer: |
PBS with 0.1% BSA, and 11% glycerol. |
| Handling Advice: |
Avoid repeated freeze/thaw cycles. |
| Storage: |
- 80°C |
| Storage Comment: |
Aliquot and store at - 70°C or lower. |
| Alternative Name: |
IFN beta |
| Synonyms: |
IFB, IFF, IFNB, IFN-beta, Ifb, Ifnb, IFNb, interferon beta 1, interferon beta 1, fibroblast, interferon, beta 1, fibroblast, IFNB1, Ifnb1. |
| Background: |
Interferons (IFNs) are proteins synthesized and discharged by host cells upon encountering pathogens like viruses, bacteria, or parasites, as well as tumor cells. They facilitate intercellular communication, activating the immune system's protective mechanisms to eliminate pathogens or tumors. Among the IFN-beta proteins, fibroblasts produce significant amounts. These proteins exhibit antiviral activity primarily contributing to the innate immune response. Specifically, two variants of IFN-beta have been identified: IFN-beta1 (IFNB1) and IFN-beta3 (IFNB3). |
| Molecular Weight: |
20 kDa |
