| Target: |
IL-18 (Interleukin 18) |
| Protein Type: |
Recombinant |
| Protein Characteristics: |
AA 36-192 |
| Origin: |
Dog |
| Source: |
E. coli |
| Purification tag / Conjugate: |
This IL-18 protein is labelled with His tag. |
| Application: |
Immunogen (Imm), positive control (PC), SDS-PAGE (SDS), western blotting (WB) |
| Characteristics: |
Interleukin-18 mouse recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 178 AA (36-192 AA) and having a molecular mass of 20.4 kDa. The mouse IL-18 is fused to 20 AA His Tag at N-terminus. |
| Purification: |
Purified by proprietary chromatographic techniques |
| Purity: |
> 95% |
| Format: |
Liquid |
| Buffer: |
The Mouse IL-18 protein solution contains 20 mM Tris-HCl pH 8 and 10% glycerol. |
| Storage: |
4°C |
| Alternative Name: |
Interleukin 18 |
| Synonyms: |
Igif, Il-18, IL-18, IGIF, ChIL-18, IL-1g, IL1F4, IL18, interleukin 18, Il18, IL18. |
| Background: |
IL-18 functions as a proinflammatory cytokine, stimulating the production of IFN-gamma in T cells. When combined with IL-12, it inhibits the production of IL-4-dependent IgE and IgG1 by B cells while promoting IgG2a production. Additionally, IL-18 binding protein (IL18BP) interacts with IL-18, exerting a negative regulatory effect on its biological activity. |
| Molecular Weight: |
17.1 kDa |
