Target: |
IL-6 (Interleukin 6) |
Protein Type: |
Recombinant |
Origin: |
Cynomolgus |
Source: |
HEK-293 cells |
Purification tag / Conjugate: |
This IL-6 protein is labelled with His tag. |
Sequence: |
Ala28-Met212 |
Purity: |
> 95% as determined by Tris-Bis PAGE, > 95% as determined by HPLC. |
Endotoxin Level: |
Less than 1EU per μg by the LAL method. |
Sterility: |
0.22 μm filtered |
Format: |
Liquid |
Buffer: |
Supplied as 0.22 μm filtered solution in PBS (pH7.4). |
Handling Advice: |
Please do not repeated freeze-thaw cycles. |
Storage: |
- 80°C |
Storage Comment: |
Valid for 12 months from date of receipt when stored at - 80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Expiry Date: |
12 months |
Alternative Name: |
IL-6 |
Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
Background: |
Interleukin-6 (IL-6) is a cytokine involved in various biological processes including the acute phase response, inflammation, hematopoiesis, bone metabolism, and cancer advancement. It interacts with both the interleukin-6 receptor and glycoprotein, exerting its effects through complex molecular interactions. |
Molecular Weight: |
22.06 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |