CD28 Antibody

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CD28 Antibody

Cat. No.: SPOOMO00044
The CD28.2 monoclonal antibody binds specifically to human CD28, a 44 kDa homodimer found on thymocytes, mature T cells, and plasma cells. CD28 acts as a receptor for CD80 (B7-1) and CD86 (B7-2), functioning as a powerful co-stimulator of T cells. Activation through CD28 enhances the expression of IL-2 and its receptor, as well as the cytotoxicity of CD3-activated T cells. These processes are crucial for regulating immune responses mediated by T cells.
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Product Details

Description: The CD28.2 monoclonal antibody binds specifically to human CD28, a 44 kDa homodimer found on thymocytes, mature T cells, and plasma cells. CD28 acts as a receptor for CD80 (B7-1) and CD86 (B7-2), functioning as a powerful co-stimulator of T cells.
Activation through CD28 enhances the expression of IL-2 and its receptor, as well as the cytotoxicity of CD3-activated T cells. These processes are crucial for regulating immune responses mediated by T cells.
Purity: Affinity chromatography
Shipping: Wet ice
Storage: 4°C
Storage Buffer: PBS, pH7.2
Species Reactivity: Human
Clonality: Monoclonal
Clone Number: CD28.2
Host: Mouse
Isotype: IgG1, kappa
Formulation: Liquid
Concentration: 1 mg/mL
Conjugate: Functional grade
RRID: AB_468926

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