| Synonym(s): |
Epidermal Growth Factor; Urogastrone; URG |
| Description: |
EGF is a powerful growth factor that promotes the growth of different epidermal and epithelial cells. Furthermore, EGF has been demonstrated to reduce gastric secretion and play a role in the healing of wounds. EGF transmits signals via a receptor called c-erbB, which belongs to the class I tyrosine kinase receptor family. This receptor also interacts with TGF-α and VGF (vaccinia virus growth factor). Recombinant Human EGF is a 6.2 kDa spherical protein composed of 53 amino acid residues, including 3 intramolecular disulfide bonds. |
| Source: |
E.coli |
| Purity: |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Molecular Weight: |
6.2 kDa |
| Gene ID: |
1950 |
| AA Sequence: |
NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR |
| Biological Activity: |
The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/mL, corresponding to a specific activity of ≥ 1 × 107 units/mg. |
| Accession Number: |
P01133 |
| Endotoxin: |
Endotoxin level is < 0.01 ng/μg of protein (< 0.1 EU/μg) |
| Crossreactivity: |
Chicken, cow, dog, hamster, horse, human, human + hamster, monkey, mouse, pig, rabbit, rat, salamander, snake, tunicate, zebra fish |
