Cat. No.: | SPODRP00685 |
Size: | |
Quantity: |
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Pricey: | Inquiry |
Target: | TNF alpha (Tumor necrosis factor alpha (TNF-α)) |
Binding Specificity: | AA 1-234 |
Reactivity: | Human, rat |
Host: | Mouse |
Clonality: | Monoclonal |
Conjugate: | This TNF alpha antibody is un-conjugated |
Application: | Enzyme immunoassay (EIA), immunohistochemistry (paraffin-embedded sections) (IHC (p)), western blotting (WB) |
Specificity: | This antibody reacts to TNF. |
Purification: | Affinity chromatography on protein A. |
Immunogen: | TNF antibody was raised against tNF (AAH28148, 1 a.a. ~ 234 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Clone: | M1-C4 |
Isotype: | IgG1 |
Concentration: | 0.5 mg/mL |
Buffer: | PBS, pH 7.2 |
Handling Advice: | Avoid repeated freezing and thawing. |
Storage: | 4°C, - 20°C |
Storage Comment: | Store the antibody undiluted at 2 - 8°C for one month or (in aliquots) at - 20°C for longer. |
Alternative Name: | TNF alpha |
Synonyms: | DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa. |
Background: | Tumor necrosis factor (TNF) is a versatile proinflammatory cytokine belonging to the tumor necrosis factor (TNF) superfamily. Primarily secreted by macrophages, TNF exerts its effects by binding to its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It plays a pivotal role in regulating a broad array of biological processes, encompassing cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. |